The first sub-forum of the 2024 Greater Bay Area Science Forum, centered on big science projects and international cooperation, was held on November 15th at Guangzhou's Bio International Island. The event brought together over 200 participants, including members of the Chinese Academy of Sciences and the Chinese Academy of Engineering, and leading experts from nearly 20 countries. They conducted in-depth discussions around the theme of "International Cooperation and Win-Win Future in the Era of Big Science".

He Fuchu is an academician of the Chinese Academy of Sciences and initiator of the international big science program on the Proteomic Navigator of the Human Body (hereinafter referred to as "π-HuB Project"). He stated that the forum would advance the scientific progress of the π-HuB Project and foster domestic and international collaboration. He highlighted the project's potential to "uncover the keys to life activities and assume a new mission in leading life sciences and human health."

Robert Moritz, chair of the nomination committee for the π-HuB Project, emphasized that the initiative is not just a Chinese national project but also a global platform attracting top-tier talent. Ruedi Aebersold, a professor at ETH Zurich, noted in his keynote speech that the project represents a significant breakthrough following the Human Genome Project, enhancing the understanding of life's foundations. He suggested that life sciences could revolutionize biomedicine, aid in building more accurate disease prediction models, and improve human quality of life.

Academician Gu Dongfeng from the Chinese Academy of Sciences shared achievements in global cooperation on research of diseases such as heart disease, diabetes, and cancer. He underscored that integrating genetic samples worldwide could help reduce cardiovascular disease risks and translate genetic insights into clinical health data.

Professor Uwe Völker from the University of Greifswald highlighted that studying proteomes could deepen understanding of disease mechanisms, noting that big science projects require substantial funding, time, and governmental support. He expressed confidence in the program's vast potential.

Participating scientists agreed that proteomics serves as the "key" to interpreting genomics, which is critical to overcoming major diseases. They called for multidisciplinary integration and the application of cutting-edge technologies to unlock new opportunities in proteomics research and advance the realization of intelligent medicine.

Source: Lingnan on the Cloud

聚焦2024大湾区科学论坛，生命科学时代需要大科学计划

2024大湾区科学论坛于11月15日在广州生物岛举行了首场分论坛——大科学计划与国际合作分论坛。论坛汇聚了来自近20个国家的顶级专家和两院院士，共200余人，围绕“大科学时代下的国际合作与共赢”主题进行了深入探讨。

人体蛋白质组导航国际大科学计划（以下简称“π-HuB计划”）发起人、中国科学院院士贺福初表示本次论坛将进一步推动人体蛋白质组导航国际大科学计划（“π-HuB计划”）的科技进展，促进国内外团队的合作。他强调，“‘π-HuB计划’有望揭示生命活动的关键，承担起引领生命科学和人类健康事业的新使命。”

“π-HuB计划”提名委员会主席罗伯特·莫里兹则指出，这一计划不仅是中国设立的国家项目，也是全球顶尖人才汇聚的平台。瑞士苏黎世理工大学教授鲁迪·艾博桑德在主旨演讲中表示，“π-HuB计划”将大幅提升人类对生命基础的理解，成为继人类基因组计划后的又一次重要突破。他认为，生命科学将为生物医学等领域带来广泛影响，并能帮助构建更准确的疾病预测模型，提升人类生命质量。

中国科学院院士顾东风介绍了国际合作在心脏病、糖尿病和肿瘤等疾病研究中的成就。他强调，全球范围的合作能够通过遗传基因样本的集成，帮助降低心血管疾病的全球风险，并将遗传风险转化为临床健康数据。

德国格赖夫斯瓦尔德大学教授奥维·沃克则表示，研究蛋白质组能更好地理解疾病机制，而大科学计划需要资金、时间和政府支持。他相信，这一计划拥有巨大的潜力。

与会科学家一致认为，蛋白质组学是解读基因组学的“密钥”，是攻克重大疾病的关键。多学科融合与前沿技术的应用将为蛋白质组学研究开辟新天地，推动智慧医学的实现。

文、图｜记者 李钢
译｜邹晓华
审｜赵凡